International generic name
Drug form and composition
Solution, oral drops. 1 ml (10%) solution contains 100 mg Tilidine hydrochloride.
Valoron is used in severe pains related to malignant diseases; spastic states,
associated with severe pain originating from the gastrointestinal tract, urinary
and biliary tracts; postoperative pain, neuralgia, and particularly neuralgia of
the trigeminal nerve.
Dosage and administration
In the adults, the drug is used orally in dose of 5 - 20 drops 3 - 4 times daily.
In children from 2 - 14 years, the dose is 1 drop per 1 year of age, 3 - 4 times
daily. In children between 11 and 14 years, the dose should not exceed 10 drops.
Hypersensitivity to the drug, pregnancy and lactation, renal failure.
Special warnings and precautions
Valoron should be used in lower doses in patients with kidney diseases, because
the elimination is disturbed. In acute myocardial infarction patients, it must be
used cautiously. Alcohol should be avoided during the treatment with this drug.
It must not be used during car driving and working with machines.
Valoron augments the central depressive action of alcohol, analeptics, analgesic
agents, barbiturates, and tranquilizers.
Headache; dizziness; orthostatic collapse; nausea; vomiting.
Valoron is a synthetic narcotic analgesic agent of the group of phenylaminocyclohexanes.
It exerts powerful analgesic action against different types of pain. Generally,
the efficiency of the drug in extero- and proprioceptive pain is higher compared
to the nonnarcotic analgesics. Its analgesic activity, as well as a number of other
effects, are related to the activation of specific opioid receptors in the central
nervous system, which regulate anti-nociception. It also exerts a spasmolytic action.
Vials of 10 ml (100 mg/ml) solution and drop device.