International generic name
Drug form and composition
Auxiliary solution for laboratory needs. One ampoule of 1 ml (3.8%) contains
31 mg Sodium citrate with 2 molecules crystalline water, equivalent to 38 mg Sodium
citrate with 5.5 molecules crystalline water. One ampoule of 5 ml (5%) contains
205 mg Sodium citrate with 2 molecules crystalline water, equivalent to 250 mg (50
mg/ml) Sodium citrate with 5.5 molecules crystalline water.
Sodium citrate with a concentration 3.8% is used in blood coagulation for clinical
laboratory examinations. Sodium citrate with a concentration 5% is applied as a
symptomatic drug in nausea and vomiting.
Dosage and administration
Sodium Citrate 3.8% is used in the clinical laboratory examinations usually in
a ratio of 1:9 (1 part Sodium citrate to 9 parts blood). Sodium citrate 5% is applied
in the following doses: Adults - 2-3 g, 3-4 times daily. Children: up to 3 months
- 0.05 g; 3 to 6 months - 0.10 g; 6 to 12 months - 0.25 g; 2 to 3 years - 0.30 g;
4 to 7 years - 0.50 g; 8 to 14 years - 1-2 g, 3-4 times daily.
It is not applied in supersensitivity to the preparation.
Special warnings and precautions
Ampoules with changed transparency of solution should not be used.
Unfavorable interactions with other drugs are unknown.
There is a danger of hypernatriemia in injured renal function or hyperaldesteronism.
Sodium citrate (3.8%), applied for laboratory needs, combines ionized calcium
in non-dissociation form. Added to blood “in vitro”, it prevents its coagulation.
Sodium citrate (5%) applied orally, relaxes the stomach mucosa and exerts antiemetic
effect in reflex vomiting, as well as a soft purgative action on the stomach.
10 or 50 ampoules of 1 ml (31 mg ) and 5 ml (205 mg).
Auxiliary solution for laboratory needs and peroral solution - 5 years.