International generic name
Drug form and composition
Solution for injection. One ampoule of 5 ml (0.9%) contains 45 mg Sodium chloride
(9 mg/ml). One ampoule of 10 ml (0.9%) contains 90 mg Sodium chloride (9 mg/ml).
The isotonic solution is applied as a solvent for preparation or dilution of
parenterally applied medicines.
Dosage and administration
The isotonic solution of sodium chloride is applied as an intravenous injection
in quantities, sufficient for the particular case.
The solution should not be applied in hypernatremia and hyperchloremia.
Special warnings and precautions
The solution should be used with care in heart failure, generalized edemas, pulmonary
edema; arterial hypertension; eclampsia; severe renal failure.
Sodium chloride increases solubility and absorption of the mercury dichloride.
Sodium and lithium ions are reabsorbed concurently in the renal tubule, which may
enhance the toxicity of the sodium* ions.
In correct application no adverse effect was seen.
The sodium ion plays an important role in maintaining of the osmotic balance
of the tissue liquids. Its concentration in the blood is almost 0.5%, which maintains
the osmotic pressure of the blood constant. The sodium ion is the most important
extracellular ion, related to the transmembrane action potential realization.
50 ampoules of 5 ml (45 mg). 50 ampoules of 10 ml (90 mg).