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International generic name
Glaucine
Drug form and composition
Coated tablets. One tablet (for children) contains 10 mg Glaucine hydrobromide.
One tablet (for adults) contains 40 mg Glaucine hydrobromide.
Indications
Dry cough of different etiology, including acute and chronic bronchitis, inflammatory
diseases of the upper respiratory tract, pneumonia, silicosis, tuberculosis, chronic
obstructive pulmonary disease, infectious diseases (pertusis, grippe, etc.).
Dosage and administration
In adults, the recommended dose is 40 mg (1 coated tablet), 3 times daily. Maximal
daily dose is 200 mg, and the single dose may be as high as 80 mg. In children,
older than 4 years the dose is 10 mg (1 tablet), 2-3 times daily. Glauvent should
be taken after nutrition.
Contraindications
Hypersensitivity to glaucine; arterial hypotension; acute myocardial infarction;
children younger than 4 years.
Special warnings and precautions
Glauvent should be used with care in patients with unstable or low arterial pressure,
as a risk of collapse exists due to the adrenolytic activity of the preparation.
The medicine should not be applied in productive cough, because it may cause retention
of the bronchial secretion and bronchial obturation. Although no data exist concerning
the embryotoxic and teratogenic effect of the Glauvent, it should be used with care
in pregnant and nursing women.
Drug interactions
No adverse drug interactions are registered so far.
Adverse reactions
Rarely in high dose following symptoms may appear: fatigue, dizziness, blood
pressure decrease, nausea, and vomiting.
Pharmacological mechanisms
Glauvent is a non-narcotic antitussive preparation with central action. The active
component of the medicine is the alkaloid from the plant Glaucinum flavum. Glauvent
depresses the cough center, causing no effect on the respiratory center. It does
not cause drug-dependence. Although the preparation exerts a weak spasmolytic effect,
it does not influence intestinal motor function and does not cause constipation.
Glauvent possesses some analgesic and anti-inflammatory actions.
Supplied
20 coated tablets of 10 mg and 40 mg.
Expiry
3 years
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