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International generic name
Combined product
Drug form and composition
Solution, eardrops. 1 ml Solution contains: 2.5 mg Nitrofural; 31.25 mg Tetracaine
hydrochloride; 87.5 mg Phenazone.
Indications
Inflammatory and purulent diseases of the external ear duct; acute inflammation
of the middle ear; following paracentesis and spontaneous perforation; chronic purulent
inflammations of the middle ear; following radical trepanation of the ear.
Dosage and administration
After cleaning of the external ear duct 4-8 drops are applied in the ear 3-4
times daily. The head should remain in lateral flexion for 3-5 minutes, and after
that the external ear duct is covered by cotton tampon. Usually 3-4 procedures are
sufficient. In infants is applied 1 drop, 2 times daily.
Contraindications
Hypersensitivity to any of preparation ingredients, hot weather, caused by Aspergillus.
Special warnings and precautions
In existence of pus, blood, and other protein substances the effect of Furotalgin
is diminished. So before application of the drops the external ear should be well
cleaned.
Drug interactions
No data for clinically significant drug interactions are available so far.
Adverse reactions
Rarely allergy reactions (contact dermatitis) to tetracaine and phenazone may
appear.
Pharmacological mechanisms
Furotalgin is a combined preparation attended for local application. It possesses
antimicrobial, analgesic and astringent actions. One of its constituents, nitrofural,
is a nitrofurine derivative, exerting bactericide and bacteriostatic actions on
the large number Gram-positive and Gram-negative pathogens, including streptococci,
staphylococci, coli-bacteria, etc. It depresses the development of the microorganisms,
resistant to sulphonamides and antibiotics. Nitrofural probably acts by inhibition
of the dehydrogenase systems in bacterial cells. Tetracaine hydrochloride is a synthetic
local anesthetic, suitable for surface analgesia, whereas Phenazone possesses analgesic
and weak astringent effects. The solvent - glycerin, dries the external ear duct
and facilitates penetration of the active components.
Supplied
Vials, containing 5 ml solution and dropper.
Expiry
5 years.
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