International generic name
Drug form and composition
Ointment. 1 g ointment contains 350: UI Vitamin A (Retinol palmitate); 400 UI
Vitamin D2 (Ergocalciferol); 10 mg Cod-liver oil; 15 mg Peru balsamum.
Deflamol is indicated in sunburns, radiation burns, thermal and chemical burns.
It is suitable in patients with hyperkeratolytic and chronic eczema and other skin
diseases as well as in frost damages. The preparation is effective in psoriasis,
in poor healing varicose ulcers and in all diseases, requiring an improvement of
the epithelization process.
Dosage and administration
In burns the preparation is spread on the sterile fold-free cloth, which is applied
on the affected region. The dressing should be changed each 2-6 days, depending
on the healing phase. In sunburns the ointment is spread directly on the affected
region 1-2 times daily.
Hypersensitivity to any of active constituents of the preparation.
Special warnings and precautions
In opened wounds is obligatory to observe sterility rules, in order to prevent
infection complications. Deflamol should not be applied in eye and other mucous
No adverse drug interactions were seen so far.
In correct observation of the recommended dose and way of administration no adverse
reactions should be expected. Tolerability to the preparation is very good. It does
not cause irritation in the place of application. Due to local application it does
not causes hypervitaminosis A and D and related complications.
Deflamol possesses a prominent epithelium-stimulating effect and in burns of
first, second and third degree contributes to formation of a soft cicatrix with
no keloids. In local application the combined preparation Deflamol exerts a favorable
effect on the affected skin region, reducing the erythema, swelling, and improving
the regenerative capabilities of the epithelium. Vitamin A is of great importance
in providing the normal functioning of the epithelium. It participates in protein
exchange of the skin and mucous membranes, as well as in synthesis of the visual
pigment rhodopsin. It possesses a prominent effect on the regeneration processes
in the skin and mucous membranes, mainly by activating the protein synthesis and
metabolism in the epithelial cells. The main physiologic function of the vitamin
D is related to the calcium-phosphate metabolism in the organism. Vitamin D improves
the cell membrane permeability to calcium ions, stimulates the specific protein
synthesis, necessary in the gastrointestinal resorption of the calcium, participates
in transportation to and deposition of the calcium in the bones. God-liver oil contains
vitamin A and vitamin D2, as well as glycerides of the oleic, palmitic and stearic
acids; bromine, iodine, and phosphate traces; cholesterol and other ingredients.
Its action depends mainly on the vitamin A and D, and no saturated fatty acid content.
Peru balsamum possesses softening and weak antiseptic effects.
Tube, containing 18 g ointment. Banks, containing 700 g ointment.