CORAZOL
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| StockNo |
Product description |
| EB0280-424-07 |
CORAZOL
VIAL 10 ML 10% SOLUTION |
| EB0280-424-31 |
CORAZOL
AMPOULE 100 MG/1 ML (10%) |
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- COMPOSITION:
Pentetrazol: 100 mg/1 ml in one ampoule
1000 mg/10 ml solution
ACTION:
According to its pharmacological properties, Corazol is similar to
caffeine and camphor. It has a direct stimulating effect on
virtually important centers in medulla oblongata: the respiratory
and the vasomotor centers. When applied in higher doses it excites
the spinal cord, the motor areas in the brain cortex, as well as
some parts of the midbrain, as a result of which clonic convulsions
may be observed. Its good water-solubility leads to quicker
absorption and to a quicker and stronger effect than that of
camphor, but it is shorter lived. The stimulating influence on
respiration, the increase of arterial pressure and the improvement
of circulation are particularly pronounced if the centers in medulla
oblongata have been suppressed. The excitatory action on the brain
and spinal cord is used for treatment of acute intoxication with
hypnotics and narcotics.
INDICATIONS:
Corazol is applied as a fast-acting analeptic in cases of collapse,
shock, asphyxia and other conditions requiring stimulation of
respiration and circulation; as a drug for interruption of narcosis;
in febrile and infectious diseases; pulmonary tuberculosis. |
CONTRAINDICATIONS:
Severe cardiac lesions; acute endocarditis; active pulmonary
tuberculosis; acute febrile conditions; predisposition to
convulsions.
SIDE EFFECTS:
The high doses may provoke convulsions.
DOSAGE AND ADMINISTRATION:
Parenterally: subcutaneously, intramuscularly and intravenously
(very slowly!) - 1 ml, 2-3 times daily. In cases of intoxication
with hypnotics and for bringing out of deep narcosis - 3-6 ml, one
half applied intramuscularly, the other half - intravenously.
Children: below 1 year - 0.15-0.2 ml s.c.
2 to 5 years - from 0.3 to 0.5 ml s.c.
6 to 12 years - 0.06-0.08
MEDICINAL FORM AND PACKAGE:
Ampoules of 100 mg/1 ml (10%) in packs of 10 and 50.
Solution (10%) in vials of 10 ml.
STORAGE:
At moderate temperature (15-30° C) in a place protected from light.
EXPIRY:
5 (five) years.
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