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ANAPYRIN
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Product description |
| EB0280-421-03 |
ANAPYRIN
TABL X 6 |
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- COMPOSITION:
Aminophenazone - 250 mg
Noramidopyrine methansulfunate sodium - 250 mg
Caffeine sodium benzoate - 100 mg
in one tablet
ACTION:
The individual components of the drug enhance reciprocally their
analgesic action. In parallel with the well-known mechanisms of
action of that group, amidophen and analgin distinguished for some
special features. Amidophen reduces the elevated body temperature by
dilating the peripheral blood vessels, and leads to intensive
release of heat with profuse perspiration; it has a temporary
inhibitory effect on the thermoregulatory center. The analgesic
effect of amidophen is due to a rise in the pain sensitivity
threshold of the thalamus and to inhibition of prostaglandin
synthesis.
Analgin ebhances the pain-relieving and antiphlogistic effect of
amidophen.
Caffeine has a potentiating action as regards the analgesic effect
of analgin and amidophen. It stimulates CNS, tonicizes the organism,
improves the working capacity, stimulates the vasomotor center.
INDICATIONS:
Headache, migraine, colds, toothache, neuralgia, arthrosis,
rheumatic pain, temperature and febrile states. |
CONTRAINDICATIONS:
The contraindications of the component drugs: agranulocytosis and
thrombocytopenia, acute and chronic allergy, diabetes,
susceptibility to edemas.
SIDE EFFECTS:
Nausea, loss of appetite, vomiting, skin rashes. Exacerbation of
ulcus disease. The function of the kidneys and the blood count
should be checked periodically.
DRUG INTERACTIONS:
It is disintegrated and sedimented after mixing with salts of heavy
metals, nitrites, iodine. It becomes moist or is liquefied after
mixing with chloralhydrate, salicytes, urotropin. Color reaction
with iron salts.
DOSAGE AND ADMINISTRATION:
Orally - 1 tablet, 2-3 times daily.
MEDICINAL FORM AND PACKAGE:
Packages of 6 tablets.
STORAGE:
At moderate temperature (15-30 C).
EXPIRY:
2 (two) years.
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