ACIDUM NICOTINICUM
| StockNo |
Product description |
| EB0280-410-01 |
ACIDUM
NICOTINICUM AMPOULE 10MG /1ML (1%) |
COMPOSITION:
Nicotinic acid 10 mg/l in one ampoule
ACTION:
Nicotinic acid has versatile effects on the human organism.
Regardless of its vitamin properties it also has a vasodilatory,
blood-cholesterol-reducing and antifibrionic effect. The reduced
level of blood cholesterol results from inhibition of the release of
free fatty acids from the adipose tissue which leads to lower level
of triglycerides and to inhibition of cholesterol synthesis. The
vasodilatory effect results from the myotropically action. The
nicotinic acid dilates the small blood vessels: arterioles,
capillaries and venulae, thus increasing the blood flow towards the
ischemic focus. The lack of effect or the deterioration of brain
blood circulation in certain cases of nicotinic acid administration
is probably associated with the presence of brain venous stasis.
INDICATIONS:
Cerebral - vascular spasms and peripheral disturbances in blood
circulation; atherosclerosis of brain vessels; diabetes mellitus;
nervous and psychic diseases; maniac-depressive psychosis,
schizophrenia, stupor, asthenic-neurasthenic phenomena. |
CONTRAINDICATIONS:
Severe forms of hypertonic disease and atherosclerosis.
SIDE EFFECTS:
The following symptoms can be observed in isolation cases: sense of
burning, itching and flushing in some skin areas (mainly of the face
and upper half of the body), dizziness, urticaria; tachycardia,
extrasystoles and hypotension; abnormal pain, intensified
peristalsis, nausea, sometimes vomiting. These phenomena are
transient (about 30-40 minutes after their appearance0, not
necessitating treatment and without sequelae.
DOSAGE AND ADMINISTRATION:
Usually intramuscularly - 0,1 or intravenously - 0,05 (very
slowly!), 1-2 times daily for 10-15 days. The subcutaneous and
intramuscular injections of nicotine acid are painful, while those
of nicotinamide are not, hence the latter is preferable for
parenteral administration in some cases.
MEDICAL FORM AND PACKAGE:
Packages with 10 and 50 ampoules of 10 mg/ml (1%).
STORAGE:
At moderate temperature (15-30 C) in a place protected from light.
EXPIRY:
5 (five) years. |