VITAMIN E

StockNo	Product description
EB0280-101-23	VITAMIN E AMPOULE 30 MG/2 ML (1.5%)

 

COMPOSITION:
Tocopherol acetate 30 mg/2 ml in one ampoule

ACTION:
Vitamin E is an antioxidant, i.e. it protects lipids, Vitamin A and a series of steroid hormones in the organism from oxidative degradation, and hence from formation of toxic metabolites or reduction of the effectiveness. It is mostly found in the germs of germinating grains (in germinating wheat predominantly), in the green parts of the plants (lettuce, spinach, lucerne, etc.), in vegetable oils and egg yolk.
It regulates the normal growth and function of the epithelium of sexual glands, as well as the development of the fetus. It is assumed to play a role in lipid metabolism and to participate in the synthesis of the compound chromatin molecule of the cell nucleus. It also has an effect on the function and structure of smooth and striated muscles (including heart muscle). The metabolism in muscles is closely associated with the catalytic functions of Vitamin E.

PHARMACOKINETICS:
The transport of Vitamin E in the blood plasma is realized through beta-lipoproteins. The usual plasma concentrations of alpha-tocopherol range between 0.7 and 1.6 mg/100 ml. It is excreted with the bile to a low extent. Administered intravenously, it is excreted with the urine, mainly unchanged and about 20-30 % as metabolites.

INDICATIONS:
Prophylactically - in habitual abortion during the critical months (III or IV) of pregnancy.
In imminent abortion, in amenorrhea, hypo- and agalactia, hypoplasia of the uterus.
In disturbances of development, in prematurely born infants, degenerative phenomena and congenital deformities, dystrophy, spasmophilia.
In neuromuscular disturbances (postpoliomyelitic paralysis), progressive muscular dystrophy (lateral amyotrophic sclerosis).
In cardiovascular diseases and disturbances in peripheral blood circulation (myocarditis, endocarditis, angina pectoris, infarction of the myocardium, atherosclerosis, thromboangitis obliterans, varicose ulcers.
In impotence, azoospermia and male sterility with a simultaneous administration of male sexual hormones.
For the treatment of refractory wounds.

SIDE EFFECTS:
The drug is well tolerated by the organism. Administered in high doses for a long time, it can induce transitory creatininuria, headache, nausea, stomach ache, sense of fatigue and weakness.

DOSAGE AND ADMINISTRATION:
It is administered intramuscularly according to schedule.
In habitual abortion, during the critical months of pregnancy, it is administered in doses of 30-50 mg/24 h for 7-14 days.
In neuromuscular diseases it is administered in a dose of 30 mg, 2-3 times weekly for several months.
To children - it is administered intramuscularly in a dose of 15-30 mg every 2-3 days.
To children - it is administered intramuscularly in a dose of 15-30 mg every 2-3 days.

MEDICINAL FORM AND PACKAGE:
Packages with 10 and 50 ampoules of 30 mg/2 ml (1.5 %).

STORAGE:
At moderate temperature (15-30° C), in a place protected from direct sunlight.

EXPIRY:
4 (four) years.